Understanding the relationship between genetic variation and biological function on a genomic scale is expected to provide fundamental new insights into the biology, evolution and pathophysiology of humans and other species The reason for the current enormous interest in SNPs is the hope that they could be used as markers to identify genes that predispose individuals to common, multifactorial disorders . If you need to genotype a low number of SNP´s in each of your samples (less than 15), than Sanger Sequencing is still the golden methodology that the customer should choose. Such small collection of SNPs occuring in genomic regions in which the frequencies of the SNP alleles differ between patients and controls. It is assumed that the SNP alleles are inherited together with the disease-predisposing alleles through the generations because they are physically close to each other. The disease-predisposing genes are genotyped in a fast and cost effective way.
























