Next-Gen

Over the past four years, there has been a fundamental shift away from the application of automated Sanger sequencing for genome analysis. Newer sequencing methods are referred to as next-generation sequencing (NGS). These newer technologies constitute various strategies that rely on a combination of template preparation, sequencing and imaging, and genome alignment and assembly methods. STAB VIDA offers, by its NGS platforms, the ability to produce an enormous volume of data cheaply — in some cases in excess of one billion short reads per instrument run. In STAB VIDA gene-expression studies microarrays are replaced by seq-based methods, which can identify and quantify rare transcripts without prior knowledge of a particular gene and can provide information regarding alternative splicing and sequence variation in identified genes. We have the ability to sequence the whole genome of many related organisms has allowed large-scale comparative and evolutionary studies to be performed that were unimaginable just a few years ago. We can provide the resequencing of human genomes to enhance your understanding of how genetic differences affect health and disease. The variety of NGS features makes it likely that multiple platforms will coexist in the marketplace, with some having clear advantages for particular applications over others